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Publications

2024

  1. Li C, Sun XN, Funcke JB, Vanharanta L, Joffin N, Li Y, Prasanna X, Paredes M, Joung C, Gordillo R, Vörös C, Kulig W, Straub L, Chen S, Velasco J, Cobb A, Padula D, Wang MY, Onodera T, Varlamov O, Li Y, Liu C, Nawrocki AR, Zhao S, Oh DY, Wang ZV, Goodman JM, Wynn RM, Vattulainen I, Han Y, Ikonen E, Scherer PE. Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex. bioRxiv [Preprint]. 2024 Jul 26:2024.07.25.605195. doi: 10.1101/2024.07.25.605195. PMID: 39211078; PMCID: PMC11360994.

  2. Zhu Q, Chen S, Funcke JB, Straub LG, Lin Q, Zhao S, Joung C, Zhang Z, Kim DS, Li N, Gliniak CM, Lee C, Cebrian-Serrano A, Pedersen L, Halberg N, Gordillo R, Kusminski CM, Scherer PE. PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels. Nat Metab. 2024 Jul;6(7):1347-1366. doi: 10.1038/s42255-024-01078-9. Epub 2024 Jul 3. PMID: 38961186.

  3. Wu X, Yu Y, Wang M, Dai D, Yin J, Liu W, Kong D, Tang S, Meng M, Gao T, Zhang Y, Zhou Y, Guan N, Zhao S, Ye H. AAV-delivered muscone-induced transgene system for treating chronic diseases in mice via inhalation. Nat Commun. 2024 Feb 6;15(1):1122. doi: 10.1038/s41467-024-45383-z. PMID: 38321056; PMCID: PMC10847102.

  4. Wang MY, Zhang Z, Zhao S, Onodera T, Sun XN, Zhu Q, Li C, Li N, Chen S, Paredes M, Gautron L, Charron MJ, Marciano DK, Gordillo R, Drucker DJ, Scherer PE. Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease. Cell Metab. 2024 Mar 5;36(3):575-597.e7. doi: 10.1016/j.cmet.2023.12.024. Epub 2024 Jan 17. PMID: 38237602; PMCID: PMC10932880.

  5. Zhao S, Li N, Xiong W, Li G, He S, Zhang Z, Zhu Q, Jiang N, Ikejiofor C, Zhu Y, Wang MY, Han X, Zhang N, Solis-Herrera C, Kusminski C, An Z, Elmquist JK, Scherer PE. Leptin Reduction as a Required Component for Weight Loss. Diabetes. 2024 Feb 1;73(2):197-210. doi: 10.2337/db23-0571. PMID: 37935033; PMCID: PMC10796304.

2023

  1. Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. PMID: 37992151.

  2. Fu Y, Ding B, Liu X, Zhao S, Chen F, Li L, Zhu Y, Zhao J, Yuan Z, Shen Y, Yang C, Shao M, Chen S, Bickel PE, Zhong Q. Qa-SNARE syntaxin 18 mediates lipid droplet fusion with SNAP23 and SEC22B. Cell Discov. 2023 Nov 21;9(1):115. doi: 10.1038/s41421-023-00613-4. PMID: 37989733; PMCID: PMC10663520.

  3. Onodera T, Kim DS, Ye R, Wang MY, Chen S, Field BC, Straub L, Sun XN, Li C, Lee C, Paredes M, Crewe C, Zhao S, Kusminski CM, Gordillo R, Scherer PE. Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells. Mol Metab. 2023 Dec;78:101821. doi: 10.1016/j.molmet.2023.101821. Epub 2023 Oct 6. PMID: 37806486; PMCID: PMC10598053.

  4. Chen X, Li H, Liu Y, Qi J, Dong B, Huang S, Zhao S, Zhu Y. Dimethyl Sulfoxide Inhibits Bile Acid Synthesis in Healthy Mice but Does Not Protect Mice from Bile-Acid-Induced Liver Damage. Biology (Basel). 2023 Aug 9;12(8):1105. doi: 10.3390/biology12081105. PMID: 37626991; PMCID: PMC10452260.

  5. He S, Li X, Mittra N, Bhattacharjee A, Wang H, Zhao S, Liu F, Han X. Microglial cGAS deletion protects against amyloid-β induced Alzheimer's disease pathogenesis. bioRxiv [Preprint]. 2023 Aug 8:2023.08.07.552300. doi: 10.1101/2023.08.07.552300. PMID: 37609338; PMCID: PMC10441288.

2022

  1. Li C, Sun XN, Zhao S, Scherer PE. Crosstalk Between Adipose Tissue and the Heart: An Update. J Transl Int Med. 2022 Sep 24;10(3):219-226. doi: 10.2478/jtim-2022-0039. PMID: 36776231; PMCID: PMC9901553.

  2. Zhu Q, Zhu Y, Hepler C, Zhang Q, Park J, Gliniak C, Henry GH, Crewe C, Bu D, Zhang Z, Zhao S, Morley T, Li N, Kim DS, Strand D, Deng Y, Robino JJ, Varlamov O, Gordillo R, Kolonin MG, Kusminski CM, Gupta RK, Scherer PE. Adipocyte mesenchymal transition contributes to mammary tumor progression. Cell Rep. 2022 Sep 13;40(11):111362. doi: 10.1016/j.celrep.2022.111362. PMID: 36103820; PMCID: PMC9533474.

  3. Zhu Y, Li N, Huang M, Chen X, An YA, Li J, Zhao S, Funcke JB, Cao J, He Z, Zhu Q, Zhang Z, Wang ZV, Xu L, Williams KW, Li C, Grove K, Scherer PE. Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention. Acta Pharm Sin B. 2022 Jul;12(7):3063-3072. doi: 10.1016/j.apsb.2022.02.020. Epub 2022 Feb 26. PMID: 35865093; PMCID: PMC9293664.

  4. Wang S, Zhu Q, Liang G, Franks T, Boucher M, Bence KK, Lu M, Castorena CM, Zhao S, Elmquist JK, Scherer PE, Horton JD. Response to Kunos et al. and Lotersztajn and Mallat. J Clin Invest. 2022 Jan 4;132(1):e156247. doi: 10.1172/JCI156247. PMID: 34981782; PMCID: PMC8718155.

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